Project 170284

AHF-EM: Acute Heart Failure - Emergency Management

170284

AHF-EM: Acute Heart Failure - Emergency Management

$300,000
Project Information
Study Type: Trial Randomized_Controlled_Trial
Therapeutic Area: Orthopedics
Research Theme: Health systems / services
Disease Area: open fractures and wound infections
Data Type: Global
Institution & Funding
Principal Investigator(s): Ezekowitz, Justin A
Institution: University of Alberta
CIHR Institute: Circulatory and Respiratory Health
Program: CIHR New Investigator
Peer Review Committee: Health Research Salary A
Competition Year: 2008
Term: 5 yrs 0 mth
Abstract Summary

Heart failure is the inability of the heart to pump adequate blood and oxygen to supply the needs of the body. Patients with heart failure have difficulty breathing, get tired easily and often have swollen legs and extra fluid in the lungs. In Canada, about 500,000 people have heart failure. Heart failure is a condition that results in frequent visits to clinic, emergency room visits, hospital stays, and has a high risk of death. Patients with heart failure have been well studied in the clinic, and when they are very sick (in hospital). However, patients that are getting sicker and need urgent attention have not been studied. They are often said to have 'acute heart failure'. This includes those needing an ambulance to take them to the emergency room. This group of patients is very important as they need urgent diagnosis, treatment, and a decision if they need to stay at the hospital. Currently, one third of patients with acute heart failure are sent straight home, and these patients are at high risk of needing urgent care again, and soon. This study will describe what happens to patients with heart failure during these first few hours of care, and in the next 3 months. By understanding how these patients are cared for, and how decisions are made, improvements to the system and potential treatments can be developed.

Research Characteristics

This project includes the following research characteristics:

Cost Effectiveness
Budget Impact
Health Technology Assessment
Resource Utilization
Implementation Science
Health System Integration
Scalability Assessment
Barrier Identification
Patient Reported Outcomes
Real World Evidence
Patient Engagement
International Collaboration
International Network
Data Sharing
Multicenter
Knowledge Translation Focus
Safety Focus
Quality of Life
Time to Event
Dose Response
Study Justification

"evaluate the efficacy of fluid lavage methods in open fracture wounds"

Novelty Statement

"first large-scale trial comparing different irrigation solutions and pressures in open fracture treatment"

Methodology Innovation

factorial design comparing irrigation solutions and pressures

Keywords
Acute Heart Failure Epidemiology Pre-Hospital Care