Project 171123

A survivorship question: Does surveillance mammography after treatment of unilateral primary breast cancer reduce the odds of dying from breast cancer?

171123

A survivorship question: Does surveillance mammography after treatment of unilateral primary breast cancer reduce the odds of dying from breast cancer?

$136,359
Project Information
Study Type: Observational Case_Control
Therapeutic Area: Oncology
Research Theme: Health systems / services
Disease Area: breast cancer
Data Type: Canadian
Institution & Funding
Principal Investigator(s): Paszat, Lawrence F
Co-Investigator(s): Holloway, Claire M; Jong, Roberta A; Rakovitch, Eileen; Sutradhar, Rinku
Institution: Institute for Clinical Evaluative Sciences-Toronto
CIHR Institute: Health Services and Policy Research
Program: Operating Grant
Peer Review Committee: Health Services Evaluation and Interventions Research - B
Competition Year: 2008
Term: 2 yrs 0 mth
Abstract Summary

We know that screening mammograms to find breast cancer save lives, from many reliable studies. However, no reliable study has ever been done to find out if the same is true about check-up mammograms for breast cancer survivors. There are many reasons why we cannot just assume that they would. One reason is that some survivors will die because of secondary cancer eventually showing up elsewhere in the body from the original cancer. Another reason is that it is often difficult to understand mammograms of women who have had radiotherapy, they might not be so accurate. We have prepared a study that would determine if survivors who have mammograms and who have breast cancer recurrence in the same breast or a new cancer in the opposite breast are less likely to die from breast cancer compared to survivors who do not have the mammograms. This is important. We know that only about 60% of survivors have these mammograms regularly. If we can show that it saves lives, we must make strenuous efforts to promote these mammograms; but if it does not save lives, it would not be appropriate to try to get every survivor to do these mammograms.

Research Characteristics

This project includes the following research characteristics:

Big Data Analytics
Cost Effectiveness
Budget Impact
Health Technology Assessment
Resource Utilization
Implementation Science
Policy Evaluation
Health System Integration
Scalability Assessment
Real World Evidence
Data Sharing
Registry Linkage
Knowledge Translation Focus
Time to Event
Study Justification

"We have prepared a study that would determine if survivors who have mammograms and who have breast cancer recurrence in the same breast or a new cancer in the opposite breast are less likely to die from breast cancer compared to survivors who do not have the mammograms."

Novelty Statement

"If we can show that it saves lives, we must make strenuous efforts to promote these mammograms; but if it does not save lives, it would not be appropriate to try to get every survivor to do these mammograms."

Methodology Innovation

nested case-control study using administrative data to evaluate the effectiveness of surveillance mammography in breast cancer survivors

Keywords
Administrative Data Breast Cancer Survivorship Health Services Research Nested Case Control Design Surveillance Mammography