Project 171165

Aging, neurofunctional reorganization and communication abilities

171165

Aging, neurofunctional reorganization and communication abilities

$701,030
Project Information
Study Type: Observational Cross_Sectional
Therapeutic Area: Aging
Research Theme: Clinical
Disease Area: aging
Data Type: Canadian
Institution & Funding
Principal Investigator(s): Joanette, Yves C; Ska, Bernadette
Institution: CIUSSS du Centre-Sud-de-l'Île-de-MontrĂ©al (MontrĂ©al, QuĂ©bec)
CIHR Institute: Aging
Program: Operating Grant
Peer Review Committee: Biological and Clinical Aspects of Aging
Competition Year: 2008
Term: 5 yrs 0 mth
Abstract Summary

This research program is about how the brain reorganizes itself to support the preservation of communication abilities during successful aging. The components of communication that will be studied are important for everyday life as they include the ability to use and process the meanings of words, to understand narratives and to understand the non-literal meanings of utterances such as indirect requests. Using the most powerful neuroimaging technologies -- including functional magnetic resonance and optical imaging -- this study will allow to describe the patterns of neural networks for communication associated with successful aging. At the same time, the impact of education and the relationship with cognitive abilities will be explored. Overall, this program will allow us to identify the optimal functional reorganization that sustains successful communication with increased age as well as the most suitable rehabilitation strategies for elderly who have to live with communication deficits due to a brain lesion.

Research Characteristics

This project includes the following research characteristics:

Implementation Science
Patient Engagement
Ethics Focus
Social Determinants
Knowledge Translation Focus
Biomarker Endpoints
Vulnerable Populations
Study Justification

"Using the most powerful neuroimaging technologies -- including functional magnetic resonance and optical imaging -- this study will allow to describe the patterns of neural networks for communication associated with successful aging."

Novelty Statement

"Overall, this program will allow us to identify the optimal functional reorganization that sustains successful communication with increased age as well as the most suitable rehabilitation strategies for elderly who have to live with communication deficits due to a brain lesion."

Methodology Innovation

using functional magnetic resonance and optical imaging to describe the neural networks for communication in successful aging

Keywords
Aging Communication Inter-Hemisphere Dynamics Magnetic Resonance Imaging (Mri) Near Infrared Spectroscopy Neurofunctional Reorganization