Project 172445

Finding the endocrine and genetic determinants of obesity: The Newfoundland study

172445

Finding the endocrine and genetic determinants of obesity: The Newfoundland study

$806,518
Project Information
Study Type: Unclear
Research Theme: Biomedical
Institution & Funding
Principal Investigator(s): Sun, Guang
Co-Investigator(s): El-Sohemy, Ahmed; Gulliver, Wayne P; Loredo-Osti, J.Concepcion; Randell, Edward W; Vasdev, Sudesh C
Institution: Memorial University of Newfoundland
CIHR Institute: Nutrition, Metabolism and Diabetes
Program: Operating Grant
Peer Review Committee: Nutrition, Food & Health
Competition Year: 2008
Term: 5 yrs 0 mth
Abstract Summary

Eating more than one needs is a major cause of human obesity. The gut produces chemicals called hormones that tell the brain how much we need to eat. If the level of these hormones is abnormal, one may eat too much leading to obesity. We think that one of the reasons why more people in Newfoundland are overweight/obese may be due to abnormal levels of these hormones. This abnormality may be genetic. We will study the role of genes in causing this abnormality in the Newfoundland population. We will measure food intake, total body fat, the level of gut hormones and relate these with any abnormality found in the genes we study. This information will help for development of medication to control abnormal gut hormone levels, food intake and obesity.

No special research characteristics identified

This project does not include any of the advanced research characteristics tracked in our database.

Keywords
Cck Food Intake And Macronutrients Genetically Homogeneous Newfoundland Population Ghrelin Gut Hormones Ppy And Pyy3-36 Snps Willett Food Frequency Questionnaire