Project 438323

Linking neonatal stress and anomalies of immune development in rats: novel insights into the origin of sex-based differences in viral infection severity.

438323

Linking neonatal stress and anomalies of immune development in rats: novel insights into the origin of sex-based differences in viral infection severity.

$100,000
Project Information
Study Type: Unclear
Research Theme: Biomedical
Institution & Funding
Principal Investigator(s): Lauzon-Joset, Jean-François
Co-Investigator(s): Kinkead, Richard; Marsolais, David
Institution: Université Laval
CIHR Institute: Gender and Health
Program: Project Grant - PA: Sex and Gender in Health Research (Bridge funding)
Peer Review Committee: Gender, Sex & Health
Competition Year: 2020
Term: 1 yr 0 mth
Abstract Summary

Psychological stress can reshape how the brain communicates with our immune system. We have reasons to believe that psychological stress occurring soon after birth rewires the immune system differently in men and women; and that these modifications may last for life. Our research is thus dedicated to understand the mechanisms that cause these differences, and how these modifications may increase the severity of infections differently in men and women. By, understanding these differences, we hope define better approaches to efficiently reduce the severity of diseases caused by infections for everyone.

No special research characteristics identified

This project does not include any of the advanced research characteristics tracked in our database.

Keywords
Developmental Origins Of Health And Disease Early Life Stress Immune Response Sex-Specific Responses Viral Infection