Project 460038

Known for many decades as an intermediary between the genetic information encoded in DNA and the proteins considered to be the main cellular effector molecules, RNA is now characterized as having a wide variety of roles in the regulation of gene expression. The considerable progress in our characterization of RNA functions advances hand in hand with our understanding of the involvement of RNA in various diseases when mutated or deregulated and with our ability to develop detection / prevention / treatment strategies based on ARN, with important consequences for human population health, but also for agriculture and biotechnology. Several examples of recent RNA effector agents have had resounding successes, but none with as much impact for mankind as the success of RNA-based SARS-CoV-2 vaccines. However, despite these advances, the majority of RNA genes are not characterized in humans (much less in other species) and we are constantly discovering new features, functions and molecular mechanisms for many, even the most studied RNAs. Moreover, until recently, experimental methodologies to measure even some of the most basic characteristics were not available for many classes of RNA. It is therefore clear that studying the biology of RNA in health and disease settings is of utmost importance. The Annual RiboClub conference brings together RNA researchers from across Canada and worldwide experts on diverse aspects of RNA biology and applications with a focus on networking, trainee education and exchange of ideas, in an inclusive and welcoming environment.