Project 461899

Investigating the relationship between endocannabinoids and pain in humans

461899

Investigating the relationship between endocannabinoids and pain in humans

$933,300
Project Information
Study Type: Unclear
Research Theme: Biomedical
Institution & Funding
Principal Investigator(s): Moayedi, Massieh
Co-Investigator(s): Atlas, Lauren; Finn, David P
Institution: University of Toronto
CIHR Institute: Neurosciences, Mental Health and Addiction
Program: Project Grant
Peer Review Committee: Behavioural Sciences - C: Behavioural Studies, Neuroscience and Cognition
Competition Year: 2022
Term: 5 yrs 0 mth
Abstract Summary

Endocannabionoids are molecules produced in the body that bind to cannabinoid receptors. These molecules have some of the same properties as cannabis products. There is a lot of evidence from animal research that endocannabinoids are involved in pain, but this has yet to be studied in humans. We will, for the first time, study the relationship between endocannabinoids and how different people feel pain. We plan to understand how endocannabinoids shape our experience of pain, and determine whether these can be used as a biomarker for different types of chronic pain.

No special research characteristics identified

This project does not include any of the advanced research characteristics tracked in our database.

Keywords
Chronic Pain Endocannabinoids Fmri Human Studies Mri Pain Quantitative Sensory Testing