Project 462107
Traffic-Related Air Pollution, Inhaled Corticosteroids and Host Defence Response in COPD
Traffic-Related Air Pollution, Inhaled Corticosteroids and Host Defence Response in COPD
Project Information
| Study Type: | Unclear |
| Research Theme: | Clinical |
Institution & Funding
| Principal Investigator(s): | Carlsten, Christopher; Mookherjee, Neeloffer |
| Co-Investigator(s): | Aaron, Shawn D; Leung, Janice; Rider, Christopher F |
| Institution: | University of British Columbia |
| CIHR Institute: | Circulatory and Respiratory Health |
| Program: | |
| Peer Review Committee: | Respiratory System |
| Competition Year: | 2022 |
| Term: | 5 yrs 0 mth |
Abstract Summary
Facts have shown that people made sick by smoking for years are made worse by bad air outside. They also often need to go to the hospital if they get a bug. One of the main drugs they take for this sickness (inhaled steroid) may change their lungs in ways that make it harder to deal with bugs, especially if they breathe in bad air. If so, this could make them need to go to the hospital more often. On the other hand, the drug (inhaled steroid) seems to help some people avoid going to hospital. We want to understand if this drug, together with bad air, makes people with lung sickness have more problems if they get a bug. To do this, we will run a study where people breathe in fresh air or bad air while taking the drug or not. We will look at the facts from this study to see if we can know how bad air and the drug together might make them get more bugs and need to go to the hospital more often.
No special research characteristics identified
This project does not include any of the advanced research characteristics tracked in our database.