Project 462629

Targeting lung microbiome for developing early detection and intervention strategies for lung cancer

462629

Targeting lung microbiome for developing early detection and intervention strategies for lung cancer

$914,176
Project Information
Study Type: Unclear
Research Theme: Biomedical
Institution & Funding
Principal Investigator(s): Lam, Wan L
Co-Investigator(s): Lam, Stephen; Lockwood, William W
Institution: B.C. Cancer Research Centre (Vancouver)
CIHR Institute: Cancer Research
Program: Project Grant
Peer Review Committee: Cancer Progression & Therapeutics
Competition Year: 2022
Term: 5 yrs 0 mth
Abstract Summary

Bacteria residing in the human lung may contribute to cancer development. This study determines whether specific changes in bacterial composition in the airways is indicative of cancer development and if the bacteria living in lung tumours are supplying essential nutrients (that cannot be produced by human cells) to support tumour growth. Knowledge gained from this project will facilitate development of innovative strategies for early detection (by detecting bacterial-related changes prior to clinical diagnosis) and early intervention of lung cancer (by targeting bacteria living in the tumour in order to starve cancer cells).

No special research characteristics identified

This project does not include any of the advanced research characteristics tracked in our database.

Keywords
Early Detection Lung Cancer Microbiome Molecular Biology