Project 465680
Clonal Hematopoiesis Regulates Anti-Tumour Immunity
465680
Clonal Hematopoiesis Regulates Anti-Tumour Immunity
$100,000
Project Information
| Study Type: | Unclear |
| Research Theme: | N/A |
Institution & Funding
| Principal Investigator(s): | Vanner, Robert J |
| Institution: | University Health Network (Toronto) |
| CIHR Institute: | Cancer Research |
| Program: | |
| Peer Review Committee: | Special Cases |
| Competition Year: | 2022 |
| Term: | 2 yrs 0 mth |
Abstract Summary
Clonal hematopoiesis is a common condition where a mutant stem cell excessively contributes to blood. We discovered that one type of clonal hematopoiesis activates the immune system to help patients fight cancer. We will test whether clonal hematopoiesis identifies immunotherapy-responsive patients and define how it supercharges immunotherapy treatments. This could help match future patients to optimal therapies and lay the foundation for new immunotherapies for cancers including leukemia and lymphoma.
No special research characteristics identified
This project does not include any of the advanced research characteristics tracked in our database.
Keywords
Blood Cancer
Hematopathology
Immunotherapy
Leukemia