Project 466263

A clinical trial is the best method of determining if one treatment is better than another. However, these trials can be time-consuming and expensive to conduct. A new way of doing clinical trials for some types of treatments is to have them done in routine care with few research staff, where the results of the trial (usually a health outcome in patients) are obtained using anonymized data collected by the healthcare system and stored in secure databases. These types of trials are called pragmatic registry trials. In general, these trials can be done in a faster and cheaper way than traditional trials. However, few researchers in Canada have the training and experience to conduct these trials. We will create a training platform to give Canadians the skills and experience needed to conduct pragmatic registry trials using existing data sources. The training platform will be offered through Canada's Health Data Research Network. Our training program will be led by Canadian faculty who are leaders in medicine, biomanufacturing, clinical trials, ethics, statistics, and implementation science. Our program will develop and support a pipeline of Canadian talent who are well-positioned to efficiently evaluate interventions-from drugs to vaccines to health technologies. The interventions will be delivered as part of routine healthcare and evaluated using routinely collected healthcare data. Our program will enable Canada to conduct better, faster, and cheaper clinical trials to prevent and manage existing and future health threats.