CIHR Projects
Browse 3370 CIHR-funded research projects
Search & Filter Projects
Showing 51-100 of 3370 projects
PI: Li, Na
Electronic Medical Records are secure, private, lifetime records containing patient-health and point-of-care histories within the healthcare system, which can be used for disease surveillance, clinic…
PI: Denis, Jean-Louis; Forest, Pierre-Gerlier; Lavis, John N
The COVID-19 pandemic underlines the importance of global health issues and the important role that public authorities at all levels of government must play to detect and contain the outbreak. Despit…
PI: Brignardello Petersen, Romina Andrea; Guyatt, Gordon H; Siemieniuk, Reed A
After the COVID-19 pandemic started, many researchers focused on assessing treatments for this disease. Global and local authorities (such as the World Health Organization (WHO) and the Public Health…
Re-thinking antibiotic prescription: a sequential mixed methods study in Quebec Dental Schools
PI: Nicolau, Belinda F; Macdonald, Mary E
Antibiotics are essential drugs for treating and curing bacterial infections in people and animals. They relieve the suffering of millions of people each year, as well as saving lives that would othe…
PI: Cavayas, Yiorgos Alexandros; Carrier, François M; Fan, Eddy; Schnitzer, Mireille E
Acute respiratory failure is the most common organ failure in the intensive care unit. Patients with acute respiratory failure commonly develop acute signs of brain dysfunction (delirium). Survivors …
PI: Ahmed, Sara; Auger, Claudine; Bleau, Michèle; Lattas, Mary; Starnino, Cindy; Thomas, Aliki
To improve outcomes for individuals with acquired brain injury (stroke and traumatic brain injury), healthcare settings are reorganizing care around the patient and providing the full cycle of care t…
PI: Presseau, Justin; Dogba, Maman A; MacPherson, Paul A
When Canadians think of donation, most are familiar with blood and organ donation. Plasma donation is another important way that Canadians can give, but most do not know much about it. Plasma is the …
PI: Barber, Claire E; Crump, Trafford
People living with the same chronic health condition may have different needs for healthcare. A persons' healthcare needs may be determined by many factors including: the number of health conditions …
PI: Fan, Eddy; Tanuseputro, Peter
Invasive mechanical ventilation (IMV) is a common form of life support provided in the Intensive Care Unit (ICU) that is increasing worldwide, particularly in the context of the COVID-19 pandemic. Up…
PI: Hutton, Brian E; Arnaout, Angel; Clemons, Mark J
With earlier cancer detection and the increased success of cancer therapies, more individuals with cancer are surviving their diagnoses, and are doing so for longer durations. Thus, increased attenti…
PI: Robaey, Philippe
In response to the COVID-19 pandemic, the switch from in-person to virtual care has resulted in an unprecedented mass adoption of home-based videoconferencing (HBVC), using personal devices (e.g., co…
Patient engagement in basic science: co-development and pilot evaluation of a novel framework
PI: Lalu, Manoj M; Fergusson, Dean A; Richards, Dawn
Patient engagement in research means patients are partners on a research team. It can have many benefits, such as ensuring research results are relevant to patients. While this practice is becoming m…
PI: Mansfield, Elizabeth A; Burkholder, Casey; Fierheller, Dianne M; Ibanez-Carrasco, Francisco; Moll, Sandra; Switzer, Sarah; Zenlea, Ian S
Arts-based, visual participatory research methods that bring together stories, images and sounds are central to many community-based health projects because they are inclusive, promote self-expressio…
PI: Mital, Seema; Barwick, Melanie A
Sudden death is a devastating outcome of hypertrophic cardiomyopathy, a genetic disease of heart muscle. It is the #1 cause of sudden death in young athletes. Sudden death can be prevented by timely …
PI: Guindon, Godefroy E; Black, Amanda; Darling, Elizabeth K
Canada remains the only high-income country with a universal healthcare system that does not include prescription drug coverage. Financial barriers to contraception have been cited as one of the reas…
Evaluating the impact of a novel acute care-based supervised injection service on patient outcomes
PI: Hyshka, Elaine
Supervised injection service(s) (SIS) are a key strategy to reduce harm from with injection drug use. They provide clean, safe spaces where people inject drugs and receive emergency care if they over…
PI: Loewen, Peter S
Atrial fibrillation (Afib) is a common type of irregular heartbeat that affects more than half a million Canadians. Patients with Afib are at much higher risk of stroke than those without Afib. Strok…
PI: Nguyen, Van Hai
In March 2020, British Columbia became the first Canadian province to introduce the 'Safer Supply' policy for opioid users. The potential impacts of this harm reduction policy have been widely debate…
PI: McIsaac, Daniel I; Jerath, Angela; Kidd, Gurlavine D; Roberts, Derek J; Saha, Tarit; Taljaard, Monica; Wijeysundera, Duminda N
More than 700,000 Canadians have blockages in leg blood vessels that can cause trouble walking, and painful sores on the ankles and feet. Blockages can also cause loss of the leg through amputation. …
PI: Thombs, Brett D; Benedetti, Andrea
Depression screening has not been shown to improve mental health. Barriers include poor-quality evidence on screening tool accuracy, on differential accuracy across cutoff scores on the same screenin…
PI: Weijer, Charles E; Taljaard, Monica
The cluster randomized trial (CRT) is an important method to generate robust evidence about clinical, health policy, health systems, and public health interventions. Unlike trials that randomly assig…
PI: Slaunwhite, Amanda K; Nicholls, Tonia L; SchĂĽtz, Christian G
People who go to correctional centres (prisons) experience poorer health compared with the general population. They have higher rates of overdose, substance use, mental illness and sexually transmitt…
Gestational diabetes mellitus (GDM), defined as high blood sugar that is first recognized during pregnancy, affects up to 1 in 6 pregnant women worldwide and carries risks for both mother and child. …
PI: Denburg, Avram E; Barwick, Melanie A; Githanga, Jessie; Gupta, Sumit
Globally, over 400,000 children are diagnosed with cancer every year, 80% of whom live in low- and middle-income countries (LMIC). Though survival rates in high-income countries exceed 80%, those in …
Intensive Care Units (ICU) are the places in hospital where the sickest patients are treated. Complications of treatment in ICU are common. We found one in four patients in Canadian ICUs have a treat…
PI: Wong, Hannah; Daly, Tamara; Ginsburg, Liane R
The COVID-19 pandemic has made clear the dire need to address underlying long-term care (LTC) workforce and workplace issues that affect resident quality of care and quality of life. These issues inc…
PI: Ambasta, Anshula; Holroyd-Leduc, Jayna M; Ma, Irene; Shih, Andrew W; Stelfox, Henry T
Blood tests are valuable tools used by clinicians to help diagnose and treat their patients. However, overuse of these tests, particularly in hospitalized patients leads to patient discomfort, disrup…
PI: Thiruganasambandamoorthy, Venkatesh
Syncope (fainting) is a common problem with 160,000 patients visiting Canadian emergency departments (ED) annually. About 16,000 (10%) will have serious underlying problems (blood clots in the lung, …
PI: Turner, Nigel E; Agic, Branka; Mann, Robert E
Gambling is common among adults in Canada. Severe problem gambling is an important public health issue because it can lead to bankruptcy, divorce, depression, and suicide and often co-occurs with sub…
PI: Mahant, Sanjay; Gill, Peter J
Urinary tract infection (UTI) is one of the most common and costly reasons why children are hospitalized. Based on limited evidence, current clinical practice guidelines recommend a screening kidney …
PI: Mayo, Samantha; Bernstein, Lori J; Edelstein, Kim
Brain metastases refer to when cancer cells spread from another place in the body to the brain. They are the most common brain cancer in adults and occur in roughly 30% of patients whose cancer does …
PI: Sauro, Khara M; Nelson, Gregg
Surgery is essential for the health and quality of life for over 1.5 million Canadians a year. However, surgery can burden patients and the healthcare system - complications are common and costly to …
PI: Carrier, François M; Chasse, Michael; Fergusson, Dean A
Liver transplantation is a life-saving procedure for patients with end-stage liver disease, but it carries a high risk of complications. About 60% of liver transplant recipients suffer from a severe …
PI: Singal, Deepa
Autism is the most common neurological disability in Canada yet there are large gaps in our understanding of how we can support autistic individuals in reaching their fullest potential. After decades…
PI: Sorensen, Janice; Crooks, Valorie A; Mithani, Akber H
Residents in long-term care homes in Canada are vulnerable to health emergencies, such as pandemics and natural disasters. This was shown during the first wave of the COVID-19 pandemic, which resulte…
PI: Quinn, Amity E
The implementation of healthcare reform in Canada has been notoriously challenging. Reforms are more likely to succeed because of timing or context changes, such as crises or actions taken by new gov…
PI: Mathews, Maria; Harris, Stewart B; Hedden, Lindsay K
The Primary Care Diabetes Support Program (PCDSP) in London, Ontario is an inter-disciplinary, team-based, primary care practice that cares for people with diabetes whose care is made more complex be…
PI: Drennan, Ian; Blanchard, Ian
In 2013 a research paper was published called the "Canadian National Emergency Medical Services Research Agenda". This paper was like a road map that tried to increase the information or scientific e…
PI: Schlenker, Matthew; El-Defrawy, Sherif R
Cataracts are the leading cause of blindness and vision loss, and can impact peoples' ability to perform daily activities, leading to decreased quality of life, higher rates of falls, hip fractures, …
Prior to the pandemic, healthcare workers (HCWs) were getting injured and burned out due to unmanageable workloads. The pandemic has intensified the need for quantifiable, effective workload manageme…
PI: Schmidt, Julia
Approximately 450 people sustain a traumatic brain injury every day in Canada; it is a leading cause of disability nationally and globally. These injuries can lead to life-long disability and health …
Health Equity Methods and Measures Considerations for Guidelines in an Age of Digital Transformation
PI: Pottie, Kevin; Courtice, Scott
Artificial intelligence and digital transformation are reshaping the next generation of healthcare. Technology presents both opportunities and threats to the health of groups of people who may suffer…
Lymphedema, a significant swelling of the arm that occurs on the side of the breast cancer, is one of the more frequent and feared complications following surgery for breast cancer. It is a lifelong …
PI: Gofine, Miriam L
In Canada, uncontrolled high blood pressure (hypertension, HTN) is a leading cause of death and is overly common among older adults (OA) age 65+. OA and clinicians report that limited access to healt…
PI: Denburg, Avram E
Advances in childhood cancer care have made cure a reality for over 80% of children in high income countries. These advances have not translated into many systems of care in low- and middle-income co…
Nos sociétés font face à des enjeux importants en matière de santé mentale et ce, accentués par la pandémie de la Covid-19 (C-19). Alors que tous les citoyens sont touchés, de larges segments de la p…
PI: Byers, Kaylee A
Over the past year British Columbians have faced numerous public health threats, including the COVID-19 pandemic, a deadly heat dome, and devastating floods. To manage and mitigate these threats, gov…
PI: Pluye, Pierre
Ce projet est innovant et conduit en partenariat avec des organisations non gouvernementales. Il vise à réduire les inégalités informationnelles. Il complète un site internet qui a été développé pour…
PI: Lange, Shannon
Opioid use and related harms have been steadily increasing in Canada, particularly in the province of Ontario. Thus, opioid use disorder (OUD) is a major public health concern. Opioid agonist treatme…
PI: Isenberg, Sarina R; Fitzgibbon, Edward J; Gilbert, Nathalie; Kornberg, Mona N; Rice, Jill L
As Canadians with life-limiting illnesses in hospital approach the end of life, the focus of their care often shifts to comfort, and they seek to return home. These transitions from hospital to home …