CIHR Projects
Browse 2384 CIHR-funded research projects
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PI: Li, Patricia T; Banerjee, Ananya T; Cherisma, Aniel; Dhalla, Irfan; Elamin, Sara; Hanley, Jill; Hui, Charles; Suleman, Shazeen
Children and Youth with Special Healthcare Needs (CYSHCN) are those who have or are at increased risk for a chronic condition such as asthma, diabetes, sickle cell, and autism. They require many serv…
PI: Birnie, Kathryn A; Jordan, Isabel; Newman, Gillian; Sun, Jenny; Wan, Michelle S; Rosenbloom, Brittany
Pain lasting months to years (called chronic pain) is a public health crisis that impacts 1-3 million youth in Canada. Youth with chronic pain experience more anxiety, depression, and negative impact…
PI: Riazi, Negin A
Schools are consistently identified as an ideal context to equitably address youth mental health (MH). However, in our research and youth engagement work, youth have expressed several barriers to acc…
We need to find the best possible ways to care for children and their families in pandemics such as COVID-19. This project will find out and share these ways, based on existing research. The project …
Previous pandemics and seasonal influenza studies have shown that in utero exposure to maternal viral infection results in a 2-7-fold increase in cognitive and psychiatric disorders in adulthood. Mor…
PI: Batthish, Michelle; Robeson, Paula; Gorter, Jan Willem
Advances in the treatment and care of individuals with complex and chronic conditions has increased the number of children surviving through to adulthood. In Canada, at the age of 18, the care of the…
PI: Stephens, Samantha; Yeh, Ann E.
Youth with chronic medical and mental health conditions (CMC) have low rates of physical activity that may stem, in part, from barriers to accessing programming and infrastructure. Our objective is t…
PI: Toulany, Alene; Mooney, Sarah; Munce, Sarah E; Stromquist, Lisa
For many youth with chronic health conditions, transition from paediatric to adult care is a challenging period. They experience negative health outcomes, disconnection from healthcare services, and …
Past traumatic events can leave lasting negative impacts on parents that may, in turn, negatively affect their children's health and development. This link is complex and not understood or addressed …
PI: Jacob, John
It is estimated that up to 75% of pediatric patients experience anxiety and distress before a new medical procedure. When not addressed, a bad hospital experience can cause future issues with coping …
PI: Kandasamy, Sujane; Anand, Sonia S; Kwan, Matthew
There are systemic barriers preventing children and youth from low income communities--particularly new immigrant and refugee families--from accessing and participating in activities and programs tha…
PI: Cleverley, Kristin D; Bartha, Christina; Davies, Julia
Approximately 1 in 5 Canadian children and adolescents have at least one mental health problem, with up to 70% continuing into adulthood. As such, the transition from child and adolescent mental heal…
PI: Cohen, Eyal; Diaz, Sanober; Orkin, Julia; Thomson, Donna
Children and youth with medical complexity (CMC) are those with complex chronic conditions and/or a neurodevelopmental disability that require specialized care to help with their health care needs. W…
Women of reproductive age are often excluded from research studies on new interventions such as medications or vaccines. As a result, information on the safety of such interventions on female reprodu…
PI: Kraus De Camargo, Olaf A; Currie, Margaret G
What's the issue? Children with disabilities and their families have been uniquely affected by measures that were put in place to limit the spread of COVID-19. Children's therapies and medical servic…
PI: Auger, Nathalie; Martel, Sylvie
There is growing evidence that the pandemic and measures meant to curb spread of the virus, such as school closures and mask mandates, had repercussions on the mental health of children and adolescen…
How do perceptions of Covid-19 risk influence health decisions in pregnancy? A mixed methods study
PI: Vanstone, Meredith; Greyson, Devon
Pregnant people have experienced many difficult circumstances during the Covid-19 pandemic, which likely affected the way they made and enacted health decisions. We know that pregnant people have a h…
The public health response to COVID-19 involved strategies to prevent person-to-person spread of the virus so that hospitals would not become overwhelmed with severely ill cases. These strategies inc…
Digital media use by young children rose during the pandemic. Too much time spent in front of screens by preschoolers has been linked to adverse health and developmental outcomes in later childhood. …
PI: Korczak, Daphne
The majority of children have reported worsening of their mental health (MH) since the onset of the COVID-19 pandemic. One important way in which the pandemic has impacted children is through disrupt…
PI: Barbic, Skye P; Mathias, Steve M; Sutherland, Jason M
We will use rich data sets at Foundry (an integrated youth services organization), the British Columbia (BC) Ministry of Health, and the Human Early Learning Partnership (an initiative to measure chi…
Chronic pain effects 1 in 5 teens in Canada. Previous studies found that teens with chronic pain are lonelier than teens without pain and that their loneliness was linked to depressed mood, anxiety, …
The COVID-19 pandemic has disrupted routines and impacted child eating behaviours. Pre-pandemic data showed that poor child nutrition and eating behaviours are associated with worsened development an…
PI: Saunders, Natasha R; Cohen, Eyal; Guttmann, Astrid
The COVID-19 pandemic triggered widespread changes in the delivery of pediatric primary care. Many primary care practices functioned at reduced capacity or switched to mainly virtual modes of care de…
The Wider Impact of the COVID-19 Pandemic on Gestational Diabetes Screening, Diagnosis, and Outcomes
PI: Yamamoto, Jennifer; Donovan, Lois E; Feig, Denice S
Gestational diabetes is one of the most common medical problems in pregnancy. It occurs when there are high blood sugar levels late in pregnancy. Gestational diabetes requires treatment during pregna…
PI: Mohamed, Ali Bedaiwy; Joseph, K. S; Lisonkova, Sarka; Yong, Paul
Recurrent pregnancy loss (RPL), defined as two pregnancy losses before 20 weeks from the last recorded period, occurs in up to 5% of all couples trying to conceive. The complexity of the pregnancy pe…
PI: Klassen, Terry P
Information about COVID-19 in children changes fast as we learn more about the disease and its wider impact. This pandemic is changing the lives of children who have COVID-19 and in other ways. For e…
PI: Yong, Paul; Anglesio, Michael S; Hanley, Gillian E; Howard, Amanda F; Mohamed, Ali Bedaiwy
Endometriosis affects ~10% of the population and is a common cause of chronic pelvic pain. It is defined as tissue resembling cells in the uterus (womb), being present outside of the uterus. In this …
PI: Shulman, Rayzel; Laur, Celia
Diabetic ketoacidosis (DKA) is a preventable and life-threatening complication of diabetes. DKA can be prevented if the symptoms of diabetes are recognized early, and children receive urgent and appr…
Participating in recommended levels of physical activity is linked to many positive health benefits in children and youth. Unfortunately, the COVID-19 pandemic has negatively impacted the physical ac…
PI: Matthews, Stephen G; Sellen, Daniel W; CHANDAK, GIRIRAJ R; Comelli, Elena M; Krishnaveni, Ghattu V; Kumaran, Kalyanaraman; Shah, Prakeshkumar; Suryanarayana, Kumar G; Wade, Mark
The health and economic burden of non-communicable diseases (NCDs) is increasing rapidly worldwide particularly in low- and middle-income countries (LMICs), where ~75% of global deaths from NCDs occu…
PI: Lye, Stephen J; Clinton, Jean M; Lule, Elizabeth L; Connor, Kristin L; Draper, Catherine E; Hung, Rayjean; Norris, Shane A
The burden of non-communicable diseases in low- and middle- income countries is significant and increasing due to several risk factors including undernutrition at early age, sedentary behaviour, poor…
PI: Majnemer, Annette; Cohen, Eyal; Costello, Carrie; Dahan-Oliel, Noémi; Filliter, Jillian H; Friedman, Jan M; Gavin, Frank; Robeson, Paula; Siden, Harold B; Wong, Logan; Barnaby, Symbia; Curran, Janet; Dlamini, Nomazulu; Glegg, Stephanie M; Goldowitz, Daniel; Laur, Celia; McCarry, Sharon; Miller, Steven P; Mora Severino, Samadhi; O'Donnell, Maureen E; Shikako, Keiko
CHILD-BRIGHT is a pan-Canadian patient-oriented research network focused on children with developmental disabilities and their families. In the past 6 years, we have created a community of over 300 r…
PI: Baillargeon, Jean-Patrice; Zhu, Guowei; Booij, Linda; Bouchard, Luigi; Fan, Jianxia; Fraser, William D; Marc, Isabelle; Masse, Louise C; Van Hulst, Andraea
The obesity epidemic in China has become a major public health concern. There is growing evidence to support the role of adverse factors before conception, during pregnancy and at early life, in the …
Previous pandemics and seasonal influenza studies have shown that in utero exposure to maternal viral infection results in a 2-7-fold increase in neurodevelopmental and neuropsychiatric disorders in …
PI: Barbic, Skye P; Mathias, Steve M; Henderson, Joanna L
Where does the health system begin and end for young people living in Canada? Early in the COVID-19 pandemic, there was a surge in TikTok users as young people sought to cope with boredom during lock…
PI: Bujold, Emmanuel; Boivin, Guy
Les données scientifiques concernant l'impact de la COVID-19 sur la grossesse sont limitées mais suggèrent une augmentation des complications telles la naissance prématurée et la prééclampsie. Parall…
Children have been underrepresented in COVID-19 research due to the low risk of becoming severely ill from the SARS-CoV-2 infection. However, the effects of COVID-19 public health measures such as sc…
Vaccinating children and youth against COVID-19 is essential to resuming essential social and economic activities. Currently, the Pfizer and Moderna COVID-19 vaccines are approved for individuals 12 …
PI: Paiement, Karine
Plus de 50% des adolescents sont insatisfaits de leur apparence au Québec. L'insatisfaction corporelle peut d'une part être une barrière à l'adoption d'un mode de vie actif, et d'autre part mener à u…
PI: Sauve, Karen A
Less than 10% of children and teens across Canada - and less than 20% globally - get enough physical activity, putting them at risk for significant lifelong health issues. Children and teens who are …
PI: Ibrahim, Isra
Non-syndromic or isolated cleft lip and palate (NSCL/P) is among the most common congenital birth defects. Clefts, that appear as gaps in the upper lip and/or the roof of the mouth (palate), occur in…
Adolescent idiopathic scoliosis (AIS) is a debilitating disorder characterized by complex three-dimensional spinal curvatures that affect ~ 4% of the population worldwide. AIS arises during adolescen…
PI: Nagaraj, Sujay
A major barrier in understanding the link between stress and chronic disease is the accurate measurement of stress in real time. The capabilities of digital devices such as smartphones and smart watc…
Babies born early, or preterm, are at risk for lifelong disability and challenges affecting their motor, communication and thinking skills. Studies using MRI pictures of the brain have shown differen…
PI: Smith, Jackson
Children who have experienced multiple types or repeated exposures to interpersonal victimization in the context of a caregiving relationship (i.e., developmental trauma) exhibit a wide range of neur…
Interactions between human breast milk compositions and genetics in childhood asthma susceptibility
PI: Fang, Zhi Y
Asthma affects over 339 million people worldwide and is the most common chronic disease among Canadian children with a prevalence of 14%. Asthma is a leading cause of hospitalizations, resulting in a…
With racial and homophobic bullying still being prevalent in schools, minority students are at risk of experiencing higher odds of mental health problems such as anxiety and depression. Although sexu…
Overview: Due to the COVID pandemic, more Canadian mothers are telling their doctors, midwives, and nurses about feelings of depression and anxiety. Community supports like peer support groups and co…
PI: Taylor, Leah
For young children with a disability, occupational therapy helps to promote independence in the activities of everyday life, also called occupations. Research has shown that participating in age-appr…