CIHR Projects
Browse 977 CIHR-funded research projects
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Showing 101-150 of 977 projects
PI: Ali, Suhad
The mammary gland undergoes complex molecular and morphological changes during the pregnancy/lactation cycle. These developmental changes within the mammary gland allow the differentiation of mammary…
Difficulties with sexual function affect up to 1/3 of women of all ages, regardless of their menopausal status, culture, and health. The World Health Organization recognizes sexual health as being a …
Identifying sex differences in the molecular mechanisms of socially-mediated pubertal suppression
PI: Holmes, Melissa M; Wilson, Michael D
Puberty is an essential developmental process in mammals. Puberty marks the onset of sexual maturation and is associated with increased incidence of depression and anxiety. Two risk factors for the d…
PI: Galea, Liisa A
Alzheimer's disease (AD) is a disease that results in the progressive loss of cells in the brain, in particular in an area important for the formation of new memories, called the hippocampus. Women a…
PI: Mishra, Suresh
Steroid hormones are essential to life. They regulate critical phases of development, such as puberty, and are essential for a number of key physiological functions in our body. Inadequate levels of …
PI: Parry, Monica J; Ceroni, Tina
The overall goal of this 2-year project is to build capacity for sex/gender uptake and patient engagement in clinical trials. A clinical trial is a research study used to compare a new drug to a harm…
PI: Murray, Melanie C; Nicholson, Valerie
In Canada, a woman's life expectancy is 4 years longer than a man's. However, for women living with HIV, not only is life expectancy 5-10 years shorter than for women without HIV of same age, but it …
PI: Medeiros, Alina
Active school travel (AST), such as walking, cycling, and rollerblading, improves children's health, air quality, and road safety. However, fewer North American children today, than in previous gener…
There is a need to examine the impact and importance of sex, gender and equity in the life cycle management of prescription drugs to support compliance with contemporary practices in developing stand…
Medical devices (i.e. pacemakers, joints, breast implants, birth control devices) are needed to extend and improve life. In Canada, the makers/distributors of new devices apply to Health Canada for a…
Let's Talk About Sex....ual Health: Exploring Young Women's Sexual Health in the Canadian Context
PI: Kennedy, V Logan
Sexual health is influenced by several different factors in a person's life, including issues related to gender and age. Women and girls have unique sexual health priorities/risks, particularly as th…
Over the course of their lives nearly 1 in 4 women living in Canada experience sexual violence. While these experiences can have significant effects on survivors' mental and physical wellbeing, sensi…
PI: Pandian, Lydia V
Maternal depressive symptoms increase after childbirth resulting in serious health issues for immigrant mothers affecting family functioning1. Studies show that the depression rate among immigrant wo…
PI: Rutherford, Leo
This project is a patient-driven study on well-being after gender affirming genital surgeries for trans men. All members of this community engagement committee (CEC) will identify as transgender men …
PI: Stuart, Gavin C
Heart disease continues to be the leading cause of premature death for women in Canada. Historically, much of what is known about the treatment and pathophysiology of the disease has been tested on m…
PI: Morin, Melanie
La vulvodynie (douleur/inconfort vulvaire) est une problématique présente chez 8 à 16% de la population féminine et affecte donc une proportion importante de femmes au Canada. La vestibulodynie provo…
PI: Green, Sheryl M
The menopausal transition is associated with a number of physical, emotional and psychological changes that have an adverse impact on a woman's functioning and overall quality of life. Sexual concern…
PI: Ahmed, Sofia B
Cardiovascular (CV) disease is the leading cause of death in women globally, highlighting the importance of studying sex-specific cardiovascular risk factors, such as exposure to estrogens. Sixty per…
Sexual health is recognized as a fundamental aspect of physical and mental health, yet adequate treatment options for sexual difficulties are scarce. Women with Sexual Interest/Arousal Disorder (SIAD…
Women who had cancer during adolescence and early adulthood (15-39 years), especially those who receive chemotherapy and or radiotherapy, may start their menopause at a younger age. Early menopause c…
PI: Brennand, Erin A
Pelvic organ prolapse (POP) is a medical condition in females where pelvic organs, such as the uterus, bladder or bowel, fall out of normal position and press into the vagina. POP will affect up to h…
Acceptability of bariatric surgery in young women with endometrial cancer: a qualitative study
PI: Ferguson, Sarah
Obesity is a significant cause of uterine cancer. Uterine cancer used to be most prevalent in women over 60; however, as obesity has been rising across the population, an increasing rate of uterine c…
PI: Bougie, Olga
Cardiovascular disease (CVD), a class of conditions affecting the heart and blood vessels in the body, remains the leading cause of premature death for women in Canada. Unfortunately, women with CVD …
PI: Kaida, Angela K; Muchenje, Marvelous
Millions of men and women living with HIV around the world want to have children and an estimated half have HIV-uninfected sexual partners. For the majority, achieving pregnancy involves condomless s…
PI: Loutfy, Mona R; Nation, Kelendria A; Persad, Yasmeen; Lacombe-Duncan, Ashley
While access to HIV-related healthcare - including HIV medications - is critical to prevent virologic failure and death, trans women living with HIV (WLWH) experience differences in their access to H…
PI: Yuksel, Nese
Hormonal changes during menopause can lead to a variety of symptoms. The use of cannabis for medical purposes has grown in Canada since legalization of recreational cannabis in 2018, with one of the …
PI: KrĂĽsi, Andrea B
Cis and transgender women living with HIV women living with HIV are over criminalized and overrepresented in Canadian prisons. This is especially true for women living with HIV who face additional he…
Can tailored nutrition programs address the unmet health needs of gay, bisexual, and trans men?
PI: Joy, Phillip
The research will explore the how tailored nutrition programs using an art-based approach and that includes a focus on body image, mental health, and stigma can address the unmet nutritional health n…
Despite their increased risk of acquiring and transmitting HIV, people who inject drugs (PID) are among those with the least access to HIV prevention and treatment. Police enforcement activities have…
This project seeks to explore the programming/services needed by Calgary's urban Indigenous youth across the gender-identity spectrum (18-24 years old) to support sexual health, identity and belongin…
PI: Wilson, Ciann L
Indigenous-Black (IB) communities have been recognized in the US for hundreds of years, but despite an over 400-year presence in Canada, they do not hold the same recognition. As a result of colonial…
It is internationally recognized that gender is one of the most influential determinants of health. This project brings together gender-diverse community members, researchers and Elders who will be l…
PI: Pruden, Harlan; Salway, Travis
Two-Spirit as an umbrella term and organizing principle that reflects diverse gender roles that have been parts of many Indigenous cultures for centuries. This project includes Indigenous and settler…
PI: Peltier, Doris J; Fong, Monique Y; Kisikaw Piyesis, Margaret L; Martin, Carrie
In 2017, Indigenous people comprised 4.9 percent of the Canadian population and 20.1 percent of new HIV infections in Canada - 31 percent of these were among Indigenous women. While the number of new…
PI: Metis Nation of, Greater Victoria
The LGBTQ2S+ Metis community is an under-researched and under served demographic in Canada. This proposal is for a multi-day gathering of LGBTQ2S+ Metis people living in the Province of British Colum…
PI: Paqtnekek Health Centre, Health Centre
We propose conducting community research on sexual and gender wellness through the seven life stages using the dimensions of physical, mental, emotional, and spiritual health in an inter-generational…
PI: Naclia, Janet
For this project, Alberta Recreation and Parks Association (ARPA) will work in collaboration with United Way of Calgary and Area to support a Treaty 7 Elders' discussion around the connections betwee…
PI: BĂ©rard, Anick
Evidence suggests that over 75% of women take at least one medication during pregnancy. Yet, data on the safety and efficacy of medications used during pregnancy is lacking due to the routine exclusi…
The purpose of this project is to develop an video to provide evidence-based education about postpartum unwanted, intrusive thoughts, images and impulses and their relationship with mental health (sp…
PI: Lau, Francis; Jollimore, Jody; Lachowsky, Nathan J
The LGBTQIA2 communities are among the most neglected populations with respect to their health needs. For this project, we want to create an implementation strategy to expand the definition, collecti…
For decades, researchers have studied sex differences and gender as health determinants. In recent years, as the realization of connections between sex and gender has deepened, we see collaboration a…
PI: Savage, Robert M
This Canadian Institutes of Health Research (CIHR) proposal is the first step in a larger project which seeks to optimize the inclusion of the lesbian, gay, bisexual, transgender, queer, intersex, an…
PI: Rich, Ashleigh J
In the context of demonstrated health disparities among transgender women living with HIV, particularly Black and Latina transgender women living with HIV, this postdoctoral research program will lev…
PI: Schang, Gauthier
Polycystic ovary syndrome (PCOS) is the most common cause of female infertility in the world. Around 10% of pre-menopausal women are affected with PCOS, making it the most common endocrine disorder i…
PI: Ritz, Stacey A; Bowdish, Dawn M; Greaves, Lorraine J; Mcarthur, Andrew G; McNicholas, Paul D; Sloboda, Deborah M; Verschoor, Chris P
Over the last 3 decades, it has become increasingly apparent that health research needs to account for gender and sex in order to apply research findings appropriately, develop technologies and polic…
Oral contraceptive pill (OCP) is a largely used contraceptive method that is often prescribed during adolescence, a time at which the brain is still developing. OCP is composed of synthetic sex hormo…
L'infertilité atteint un couple canadien sur six. Dans plus du quart des cas, aucune cause n'est mise en évidence, c'est ce qu'on appelle l'infertilité inexpliquée. Malheureusement, les traitements i…
PI: De Denus, Simon; Dubé, Marie-Pierre; Leclair, Grégoire
In general, women have a higher risk of adverse drug reactions than men. This is believed to be because women may present higher blood concentrations of drugs than men when they are given a specific …
Many differences between males and females arise between conception and birth. As the main regulator of fetal growth and development is the placenta, many of these differences arise because male and …
PI: Boreskie, Kevin
Current methods of assessing cardiovascular disease (CVD) risk in women underestimate their risk. A suggested method of improving CVD risk management is the addition of frailty assessments as vital s…