CIHR Projects
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PI: Arocha, Jose F; Donelle, Lorie F; Hoffman-Goetz, Laurie
The Internet is increasingly used as a source of health information, with older adults representing the fastest-growing user group. Individuals search the Internet for information they use to support…
PI: Roy, Elise; Bruneau, Julie
Malgré certaines améliorations observées depuis quelques années, les épidémies du VIH et de l'infection due au virus de l'hépatite C (VHC) liées à la consommation de drogues sont toujours très active…
PI: Brown, Thomas G; Nadeau, Louise; Ouimet, Marie Claude
This proposal describes the next steps in a pioneering integrative and transdisciplinary research program, initiated in 2002, to reduce driving while impaired by alcohol and other drugs (DWI). We ext…
South Africa has the highest absolute number of people infected with HIV/AIDS in the world. Although testing and treatment centres are available throughout the country, testing rates remain low, and …
Addressing mental health needs in the face of AIDS: A South African Perspective (working title)
Current research has unequivocally proven that to change outcomes for individuals living with HIV/AIDS, multi-disciplinary approaches are our best hope. For individuals affected by HIV/AIDS, the stre…
PI: Otis, Joanne; Rousseau, Robert
Des données récentes indiquent que parmi les hommes ayant des relations sexuelles avec des hommes (HARSAH) qui sont séropositifs au VIH, un nombre important ignore leur statut sérologique. L'ignoranc…
Use of ampethamine-type substances and HIV/STI transmission among female sex workers in Cambodia
Cambodia is the country in Southeast Asia that is the most affected by the HIV epidemic. Factors contributing to the epidemic include poverty, sexually transmitted infections (STI), trafficking of wo…
Participation in physical activity can provide potential health enhancing benefits however only 49% of Canadians achieve the recommended level of physical activity required to benefit their health. M…
PI: Elgar, Frank J
Depression and alcohol abuse are common health problems in Canada. Unfortunately, these problems also tend to run in families. Millions of children are put at risk for mental health problems as resul…
Genetic Epidemiology of Osteoporotic Fractures; From Susceptibility Genes to Susceptible Populations
PI: Richards, Brent
Osteoporotic fractures are a common and debilitating problem, which are strongly influenced by our genes. Although many environmentally determined risk factors for osteoporotic fractures have been id…
PI: Karp, Igor
The ability to assess an individual's risk of lung cancer can have important implications for public health, clinical medicine and for individual decision-making regarding lifestyle changes. We will …
PI: Hodges, Nicola J
In British Columbia 2 in every 1000 births are of children with Down syndrome. This is a genetic disorder which results in an array of symptoms including mental and sensory-motor difficulties. People…
Can we predict adult health based on youth characteristics and experiences? This question is addressed in an interdisciplinary program of research that will use six waves of data to follow a cohort o…
PI: Haque, Nasim
Nearly one in five Canadian adults experience a mental illness and this illness disproportionately affects people living in poor neighbourhoods. The total direct and indirect cost of mental health pr…
Because people are living longer they are now living long enough to develop conditions that require a wide variety of surgeries including, for instance, knee and hip replacement. Worldwide, over 200 …
In recent years, many public health agencies have started to operate automated surveillance systems. Due to the large volume of data, surveillance analysts are not able to review all data manually. I…
An Integrated Approach to Blood Biomarker Discoveries in Chronic Obstructive Pulmonary Disease.
PI: Man, S.F. Paul; Sin, Donald
Chronic Obstructive Pulmonary Disease is a very common chronic disease with huge societal and personal impact. This study will provide an integrated approach to create a bank of biomarkers (simple bl…
Investigating the Role of Self-Report Bias in Health Inequalities Between and Within Countries
PI: Harper, Samuel
As people in many countries are living longer, health conditions that are not usually fatal, such as mental disorders, arthritis, and vision and hearing problems are becoming increasingly important a…
PI: Eurich, Dean; Majumdar, Sumit R
Pneumonia (serious infection of the lungs) is a common reason for hospitalization and in this day and age is still the 6th leading cause of death in Canada. Despite how common and costly it is, surpr…
PI: Tamblyn, Robyn M
Medications are the most frequent causes of preventable adverse events including illness, and death. Drugs do not have complete information on safety and effectiveness at the time of market approval.…
PI: Riddick, David S
Hormones are the chemical messengers of the endocrine system that regulate the body's normal functions, and they are also critical in playing adaptive roles in response to events outside the body. So…
Advancing Knowledge Translation: Using Networks to Stimulate Interactions for Public Health Advocacy
PI: Kothari, Anita R
Health issues are becoming more and more complex, and require community agencies to work together for lasting solutions. For example, ensuring food safety requires local food producer groups, retaile…
PI: Uetrecht, Jack P
Drugs can cause serious side-effects. Some of these side-effects are mediated by the immune system (a type of allergic reaction) and are very unpredictable. We are trying to understand the basic of t…
The BeAMS Study. Long-term Benefits and Adverse Effects of Beta-interferon for Multiple Sclerosis
Multiple Sclerosis (MS) is a relatively common disease of the brain and spinal cord, leading to disability, severe fatigue, and coordination problems; its cause is unknown. Canada has some of the wor…
PI: Kulig, Judith C
The unique spiritual beliefs among Low German Speaking Mennonites (LGS) and their large population in Canada points to the need to understand their beliefs and practices about death and dying in orde…
Infections with meningococcal bacteria are rare but cause serious, fatal illness. Young children ages 0-5 years are at the highest risk for these infections. Prevention is desirable, as about 15% of …
PI: Menzies, Richard
Although effective medications to treat and prevent Tuberculosis (TB) have been available for over 60 years, TB remains the most important infectious cause of mortality among adults in the world. One…
PI: Bhandari, Mohit; Guyatt, Gordon H
Traffic accidents ranked among the top 10 causes of global disability in 1990. By 2020, disability from traffic accidents is estimated to rank in the top 3 of all cause disability from disease - seco…
PI: Hall, Wendy A
Infant behavioural sleep problems affect up to 50% of infants and contribute to adverse effects for infant development and parents' health. A significant proportion of infants do not grow out of slee…
Few interventions can help breast cancer patients improve their physical strength, stamina, and overall well-being during chemotherapy. Literature is now suggesting that physical activity (PA) is a s…
Few interventions can help breast cancer patients improve their physical strength, stamina, and overall well-being during chemotherapy. Literature is now suggesting that physical activity (PA) is a s…
PI: Ridde, Valéry
L'objet de notre programme de recherche réalisé en Afrique de l'Ouest vise comprendre si l'abolition du paiement direct des soins de santé est une stratégie efficace pour améliorer l'équité d'accès a…
PI: Kaplan, Gilaad G
Crohn's disease and ulcerative colitis are incurable diseases that affect a patient's gut. The causes of these diseases are not known. However, it most commonly occurs in industrial countries such as…