CIHR Projects
Browse 977 CIHR-funded research projects
Search & Filter Projects
Showing 1-50 of 977 projects
PI: Durocher, Keri
Despite being at higher risk of developing common mental health disorders, such as anxiety and depression, women are significantly more likely to experience barriers in accessing specialized mental h…
PI: Perez-Brumer, Amaya G; Konda, Kelika A; Silva-Santisteban, Alfonso
Venezuelan migrants who engage in sex work (VSW) face unique biosocial stressors that render them in urgent need of tailored HIV and STBBI prevention and care services; yet this population remains un…
PI: Numer, Matthew S; Holmes, Dave
Sexualized drug use (SDU) is common among gay, bi, trans, Two-Spirit, and queer (GBT2SQ) men, and our recent CIHR study found that many GBT2SQ men have experienced sexualized violence (SV) when they …
PI: Etowa, Josephine B; Brown-Shreves, Danielle; Massaquoi, Notisha M; Omorodion, Francisca I
In Ontario, African, Caribbean, and Black (ACB) women are overrepresented among new HIV diagnoses. This overrepresentation of ACB women is believed to be in part due to social and structural factors,…
PI: Lauzon-Joset, Jean-François
Psychological stress can reshape how the brain communicates with our immune system. We have reasons to believe that psychological stress occurring soon after birth rewires the immune system different…
PI: Abramovich, Alex
Transgender adolescents and youth experience high rates of stigma, discrimination, and identity-based rejection leading to poor health outcomes, including suicidality, substance use, depression, and …
The issue: Sexual and gender minorities (SGM)¬-including lesbian, gay, bisexual, transgender, queer and Two-Spirit individuals-experience elevated rates of suicide-related outcomes (i.e., suicide tho…
PI: Bennett, Steffany A; Cuperlovic-Culf, Miroslava
Seventeen years ago, Citron called the lack of therapeutic options for Alzheimer's disease (AD) the "biggest unmet medical need in neurology". Today, we still do not have the necessary drugs to prope…
PI: Aoyama, Kazuyoshi; Ray, Joel G
Over the past two decades, an increasing number of women in Canada have experienced serious health issues because of infection during pregnancy, during childbirth and after childbirth. This is called…
Study of sex-specific biological factors underlying cognitive function and cardiovascular outcomes
PI: Dubé, Marie-Pierre; Gagliano Taliun, Sarah A
The cardiovascular and nervous systems (heart and brain) are linked, but the relationships between the two systems are largely unexplored. Adult-onset conditions of the heart and the brain affect wom…
PI: Logie, Carmen; Kyambadde, Peter; Mbuagbaw, Lawrence C
THE ISSUE: Globally, there are 38 million people living with HIV (PLHIV)-two-thirds of whom live in sub-Saharan Africa. HIV prevalence is highest in the regions most impacted by climate change and ex…
PI: Sun, Louise; Etherington, Cole
Heart surgery is a complex and commonly performed procedure used to treat patients with critical disease. It is life altering in that patients may have restoration of quality and quantity of life or …
PI: Lorway, Robert R; Becker, Marissa; Kimani, Joshua; Mckinnon, Lyle R; Shaw, Souradet Y
Early mischaracterization of HPV as a women's health problem-referred to as the 'feminization of HPV'-largely ignored high risk for anal HPV-related infections and cancers among men who have sex with…
PI: Rebic, Nevena
HEALTH PROBLEM: Even though transgender and gender diverse people are more likely to have poorer mental and physical health, they face more barriers to getting the care they need. Likewise, the lack …
PI: Malik, Mannat
Black and Latina transgender women are disproportionately impacted by HIV and poor mental health (e.g., depression and suicide). A growing body of research demonstrates that experiencing stigma relat…
PI: Vedel, Isabelle
The COVID-19 pandemic has highlighted the importance of planning more equitable care, especially for vulnerable population such as persons with dementia and their care partners. Developing evidence-b…
PI: Logie, Carmen; Hakiza, Robert
THE ISSUE: The COVID-19 pandemic has exacerbated refugee health disparities. Our team documented high food insecurity, depression, alcohol use, and unmet HIV prevention needs with urban refugee youth…
PI: Côté, Sylvana; Dennis, Cindy-Lee E; Mâsse, Benoît R
Women of child bearing age have had the largest increase in anxiety and depressive disorders of all age groups since the onset of the pandemic (Lancet, 10/21). As documented in over 300 studies and 1…
Alcohol use disorders and the risk of suicidal behaviour: A sex/gender-specific investigation
PI: Lange, Shannon; Orpana, Heather M
Suicide is a leading cause of death in Canada. Despite suicide prevention being a top priority both nationally and internationally, little to no progress has been made in reducing the suicide mortali…
PI: Brennand, Erin A
Sex-and-gender based disparities are known to occur in health care. Research has shown female patients experience different care for similar conditions and presentations when compared to males. Sex-a…
PI: Community-Based Research Centre, .; Lachowsky, Nathan J
2SLGBTQQIA+ people in Canada have unique needs and experience barriers within sexual and reproductive health care (SRHC), where many providers have little knowledge of our experiences, bodies, or sex…
PI: WisdomToAction, .; Salway, Travis
2SLGBTQ+ young people across Canada experience high levels of street harassment and other forms of public gender-based violence. According to a 2018 Statistics Canada study, 76% of bisexual women and…
PI: Egale Canada, .
Two-spirit, lesbian, gay, bisexual, trans, queer and intersex (2SLGBTQI) older adults face increased barriers to accessing healthcare services. These barriers include Canadian healthcare systems and …
In the past two decades, a number of countries in Europe, North America, and Asia have adopted "end demand" criminalization frameworks for the sex industry (also known as the "Swedish Model" or "Nord…
PI: GRIS-Montréal, .; Houzeau, Marie; Lavoie, Kévin; Vallerand, Olivier
Le GRIS-Montréal compte plus de 250 bénévoles qui témoignent de leurs réalités en tant que personnes LGBT dans le cadre d'ateliers de sensibilisation. Ces ateliers interactifs, réalisés par un duo de…
PI: AIDS Committee Cambridge, Kitchener & Waterloo; Cameron, Ruth; Davis, Contessa; Coleman, Todd A; Khan, Maryam; Wilson, Ciann L
In 2016, the AIDS Committee of Cambridge, Kitchener, Waterloo, and Area and the local Rainbow Community Council conducted an online needs assessment of local lesbian, gay, bisexual, and queer people …
This exploratory research project seeks to understand the sexual health knowledge and needs of LGBT+ adults labeled/with developmental and intellectual disabilities in Alberta, Canada. There is a gro…
PI: Rueda, Zulma V; Haworth-Brockman, Margaret J; Keynan, Yoav
In Manitoba, injection drug use is the most common mode of HIV transmission since 2018. Those who inject drugs are more likely to test positive for HIV, syphilis and Hepatitis C, often at the same ti…
PI: Grace, Daniel; Gahagan, Jacqueline C; Gilbert, Mark P; Kia, Hannah; Lachowsky, Nathan J; McCready, Lance T
We propose the development of a comprehensive training and mentorship platform focused on community-based interventions to support the health of 2SLGBTQ+ populations across the lifecourse. The S2LGBT…
PI: Metcalfe, Amy L; Brennand, Erin A; Gordon, Jennifer L; Van Lieshout, Ryan J
Our vision is to create an interdisciplinary training program that brings together clinical and graduate trainees, post-doctoral fellows, early career researchers, and established researchers with a …
Despite being at higher risk for sustaining a mild traumatic brain injury (mTBI), reporting greater symptoms following injury, and having longer recovery trajectories, females continue to be understu…
PI: Ford, Victoria
Female urogenital issues are one of the most common burdens to primary health care systems. The launch of the influential UK Women's Health Strategy and recent calls for evidence highlight the need f…
PI: Speed, Kelsey
Women and non-binary people who use illegal drugs (e.g., heroin, cocaine) in Canada are at risk of illness and death, and have trouble accessing health and social services. To address these harms, ma…
PI: Smith, Peter M
Gender is a multidimensional construct. While measures to assess some dimensions of gender, such as gender roles and expectations, have been developed, concurrently measuring all dimensions of gender…
PI: Belleville, Geneviève; Ouellet, Marie-Christine
There are 636,000 self-reported cases of sexual assault (SA) in Canada annually, and nine out of ten persons who have experienced sexual assault (SA) are women. An alarming paradox is that while pers…
Twenty years ago, Citron called the lack of therapeutic options for Alzheimer's disease (AD) the "biggest unmet medical need in neurology". Today, we still do not have the necessary drugs to properly…
PI: Aoyama, Kazuyoshi; Ray, Joel G
Over the past two decades, an increasing number of Canadian women have experienced serious health issues due to, and/or made worse by, pregnancy. This is known as "severe maternal morbidity" (SMM). S…
Vascular diseases such as heart attacks and stroke are the main cause of death in females, and females diagnosed with these diseases are more likely to die from them than males. Despite this, most st…
PI: Parry, Monica J; Mullen, Kerri-Anne
The leading cause of premature death for Canadian women is cardiovascular disease. Since 2017, death due to cardiovascular disease has increased in women in two high income countries: Canada and the …
PI: Parry, Monica J; Beleno, Ron; Nissim, Rinat; Peter, Elizabeth H
About 28% of Canadians are in unpaid caregiving roles and they are the backbone of the Canadian healthcare system. Unpaid caregivers provide 75% of care services at home. Unpaid caregiving can impact…
PI: Lorway, Robert R; Becker, Marissa; Kimani, Joshua; Mckinnon, Lyle R; Shaw, Souradet Y
Early mischaracterization of HPV as a women's health problem-referred to as the 'feminization of HPV'-largely ignored high risk for anal HPV-related infections and cancers among men who have sex with…
PI: Ghabrial, Monica
Trans and non-binary (TNB) people are individuals whose gender does not correspond with the gender they were assigned at birth. TNB people - in particular, people of Colour (PoC) - experience minorit…
PI: Howren, Alyssa M
Depression affects over 264 million people worldwide and is 2 times more common among women than men. However, men have an increased tendency for violent behaviour, substance use, and their rate of s…
The BuddyUp mental health e-intervention: Engaging men through social connection and mutual help
PI: Sharp, Paul
Men face barriers to seeking help for mental health challenges that contribute to low uptake and retention of clinical supports and treatment. While much work has been done to understand gender-relat…
PI: Closson, Kalysha
Gender equity is a basic human right, and essential for gender equality, global health equity and development, yet there exists few to no measures to evaluate progress in global gender equity efforts…
PI: Scime, Natalie V
Autoimmune diseases are chronic immune-mediated conditions that are up to 9 times more common in females compared to males, and are a leading source of disability and premature death in women. Knowle…
PI: Bergeron, Sophie; Dion, Jacinthe
Having a strong connection with a romantic partner is a greater predictor of mortality than smoking, alcohol consumption, and obesity, suggesting that close relationships are the cornerstone of life …
Transgender and gender diverse (TGD) people have been largely excluded from sexual health research, though as many as 1/200 adults are TGD. Many transfeminine (tF) individuals choose to undergo the g…
PI: Kimmins, Sarah
Globally the prevalence of diabetes, obesity, infertility and other chronic diseases are on the rise. These increases have occurred at rates that cannot be due to changes to the DNA. Instead it is li…
PI: Kimmins, Sarah; Dumeaux, Vanessa
Globally the prevalence of diabetes, obesity, infertility and other chronic diseases are on the rise.These increases have occurred at rates that cannot be due to changes to the DNA. Instead it is lik…