CIHR Projects
Browse 2884 CIHR-funded research projects
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PI: Garg, Amit; Basile, Erika; Bhatia, Rajan S; Clemens, Kristin K; Dixon, Stephanie N; Ethier, Jean-Francois; Fowler, Robert A; Gagnier, Joel J; Garrison, Scott R; Grimshaw, Jeremy M; Hohl, Corinne M; Ivers, Noah M; Jairath, Vipul; James, Matthew T; Jerath, Angela; Katz, Alan; Krzyzanowska, Monika K; LeBlanc, Annie; Lee, Douglas S; Mcalister, Finlay A; McGrail, Kimberlyn M; McIntyre, Lauralyn A; Mittmann, Nicole; Naylor, Kyla; Presseau, Justin; Schull, Michael J; Sontrop, Jessica M; Spence, Jessica; Swartz, Richard; Taljaard, Monica; Tangri, Navdeep; Udell, Jacob A; Weijer, Charles E; Zwarenstein, Merrick F
A clinical trial is the best method of determining if one treatment is better than another. However, these trials can be time-consuming and expensive to conduct. A new way of doing clinical trials fo…
PI: Bacon, Simon L; Alberga, Angela S; Campbell, Tavis S; Carlson, Linda E; Gordon, Jennifer L; Jung, Mary E; Lavoie, Kim; Locke, Sean R; Presseau, Justin; Rash, Josh A; Vallis, Micheal T
High-risk human behaviours, such as poor medication and vaccination adherence, low quality diets, physical inactivity, smoking, excess alcohol consumption, are key causes of most chronic diseases. Ev…
PI: Parpia, Sameer; Golchi, Shirin; Heath, Anna; Lee, Shun Fu; Sajobi, Tolulope T; Thorpe, Kevin E; Wong, Hubert H
Clinical trials are human scientific experiments designed to answer specific questions about biomedical and behavioural interventions. The quality of a clinical trial (CT) depends, among other aspect…
PI: Mahmood, Bushra
Background COVID-19 and pandemic response measures implemented to limit its spread have resulted in various indirect health impacts due to the disruption of many preventative, diagnostic, and managem…
Multimorbidity is when an individual has two or more chronic diseases. But, behind this simple definition lies a complex phenomenon. Chronic diseases interact, and their combined health impacts can b…
PI: AbuRaed, Ahmed G
The illicit drug overdose crisis in North America has had a profound impact on individuals, families and communities, often leading to premature loss of life and lowering of life expectancy. Since 20…
There are well established links between access to transportation and health for older adults. Access to transportation is essential for older adults to connect with family and friends, and to access…
PI: Hood, Kalli M
Lead exposure is an ongoing public health concern due to the association with cognitive deficits and neurodevelopmental disorders, particularly in children and infants. While several vectors of expos…
Occupational heat stress directly threatens workers' ability to live healthy and productive lives. The heat stress guidance provided to Canadian workplaces currently prescribes a one-size-fits-all ap…
Since 2014, the Canadian Red Cross (CRC) has partnered with the South Sudan Red Cross (SSRC), supported by Global Affairs Canada, to improve reproductive, maternal, neonatal and child health (MNCHH) …
Le Groupe d'experts intergouvernemental sur l'évolution du climat (GIEC) prévoit qu'avec les changements climatiques, nous verrons une augmentation dans le nombre, l'intensité et la durée des événeme…
PI: Milloy, Michael-John S; Reddon, Hudson; Walsh, Zach
There is active popular interest and a growing public health need to better understand the impacts of cannabis on Canadians in the era of legalization and regulation. The impacts of this policy frame…
Predictors and impact of postoperative pain after same-day surgery - a prospective cohort study
In Canada, >1.8 million same-day surgeries are performed annually and are generally considered lower risk interventions. Within a few hours after same-day surgery, patients are sent home and are requ…
We designed and launched the Alberta Cancer Exercise (ACE) program, a five-year hybrid effectiveness-implementation study to evaluate the benefit of an Alberta-wide cancer-specific community-based ex…
PI: Kozak, Robert A; McGeer, Allison J
The Omicron wave provided real-world evidence that even when vaccine rates are high, a vaccine mismatch can lead to decreased efficacy. As we move towards the virus become endemic, we will need to pa…
PI: Montesanti, Stephanie R; Wells, Lana M
During the COVID-19 pandemic, there was a surge in domestic and sexual violence (DV/SV). Although many organizations were collecting information on DV/SV, there was no centralized structure to combin…
Addressing the COVID-19/malaria interface at health centres in the Democratic Republic of Congo
With the COVID-19 pandemic jeopardizing two decades of progress against malaria in Africa, approaches to supporting health workers on the frontlines of managing both diseases are urgently needed. Hea…
PI: Boyd, Jade
British Columbia (BC) continues to grapple with an overdose epidemic that has largely been framed as a men's public health crisis. Little has been said regarding how women (transgender, Two-Spirit an…
COVID-19 in working age Canadian adults: Long-term follow up of infections and immune responses
COVID-19 infections continue to impact our lives and economy despite vaccinations and other protective practices. Many of the infections are caused by variants to the original virus. Due to the abili…
PI: Snider, Carolyn; Bailey, Annette A; Gomez Jaramillo, David; Sharpe, Tanya L
Twenty percent of those who are injured by violence will be injured again within the next year. Hospital-based violence intervention programs (HVIP) offer an opportunity to use the time of reflection…
PI: Reimer-Kirkham, Sheryl; Astle, Barbara J; Ero, Ikponwosa; Mogale, Ramadimetja S
Until recently, occulocutaneous albinism has received little attention as a global human rights concern. However, recent attacks, mutilation and murder of persons with albinism in Sub-Saharan Africa …
PI: Cook, Richard J
The digitization of health records mean that large volumes of data are now available for scientists to study disease processes, obtain real-world evidence regarding the effect of treatments, and to u…
PI: Larouche, Richard; Tremblay, Mark S
Physical activity is essential for healthy child development, yet 80% of youth are not active enough and we lack information about activity levels of young children. Current physical activity questio…
People with food insecurity lack regular access to enough safe and nutritious food for normal growth and an active and healthy life. Food insecurity has been increasing steadily in Canada. Food insec…
PI: Schnitzer, Mireille E; Talbot, Denis
Fast research designs have been proposed for estimating how well different vaccines protect against disease, severe disease, hospitalization, and death from COVID-19. In fact, ongoing study is needed…
PI: Senn, Charlene Y; Peitzmeier, Sarah M
Sexual assault is a serious problem at universities with conservative estimates of 1 in 5 women students experiencing sexual assault before they graduate. To date, only the small group in-person EAAA…
PI: Bogoch, Isaac
Schistosomiasis is a parasitic infection that affects over 200 million people worldwide with more than 90% of the global burden in African settings. Children and the impoverished are disproportionate…
PI: Card, Kiffer G; Benoit, Cecilia M; Chen, Frances; Nicholson, Valerie
In 1942, Canada's first Food Guide provided public health guidance for wartime food rationing. These guidelines have since evolved to be a vital source of nutritional guidance for Canadians. Decades …
Gestational diabetes mellitus (GDM), defined as high blood sugar that is first recognized during pregnancy, affects up to 1 in 6 pregnant women worldwide and carries risks for both mother and child. …
The Pan American region is highly diverse. The region comprises Canada, the United States (US), the Francophone and Anglophone Caribbean, and 21 other Spanish speaking countries or territories from t…
PI: Brassard, Paul
Tuberculosis (TB) disease is a serious global health threat claiming millions of lives every year. Although curable, resistance of Mycobacterium bacteria to antibiotics may develop. In addition, prol…
Clinically apparent Helicobacter pylori infection and the risk of incident Alzheimer's disease
PI: Brassard, Paul
Given the global ageing population, Alzheimer's disease (AD) numbers are expected to triple in the next 40 years. However, there remains a lack of effective treatment options for this disease. Curren…
PI: Boyd, Jade
British Columbia (BC) continues to grapple with an overdose epidemic that has largely been framed as a men's public health crisis. Little has been said regarding how women (transgender, Two-Spirit an…
PI: Kershaw, Paul W; Hennessy, Trish
Background: Research shows that government spending on social programs (e.g., poverty reduction, housing, childcare, etc.) has a stronger association with population health than does public investmen…
PI: Staples, John A
People who use illicit drugs are more likely to discharge themselves from hospital even when their doctor tells them they require ongoing hospital care. This is called 'discharge against medical advi…
PI: Lavoie, Kim; Bacon, Simon L
Despite the fact that Canadians, and people around the world are 'done' with COVID-19, the World Health Organization, the US Center for Disease Control and Health Canada are all projecting that new v…
PI: Bayoumi, Ahmed M; Dodd, Zoe; Firestone, Michelle
Decriminalization of unregulated (illicit) drugs is the next "big" drug-related policy change and both Vancouver and Toronto have started processes to request exemptions from federal drug laws so tha…
PI: Pfaff, Kathryn A
People living in border cities face barriers connecting to healthcare and health care resources. The cities of Windsor, Ontario and Detroit, Michigan are border cities that have been described as "do…
Le but de cette proposition est de circonscrire les balises liées à engager une conversation sur les DMA, au moment opportun, et ainsi de mieux comprendre les défis liés au respect à l'autonomie déci…
PI: Mubareka, Samira
Many infectious diseases are zoonotic in origin. These pathogens may spillover into other species and cause disease. Zoonotic viral pathogens include influenza virus, Ebola virus, Zika virus, severe …
Healthcare providers, researchers, criminologists, sociologists, community groups, injury prevention organizations, advocacy groups, and victims of firearm violence will gather for a series of virtua…
PI: Kestens, Yan
Cities play an increasingly decisive role in building a healthier and more equitable society. Through policies, programs, and built environment interventions, they have the potential to address major…
PI: Storey, Kate E; LĂ©vesque, Lucie
The country of Antigua and Barbuda has identified a need to focus its health promotion and chronic disease prevention efforts towards children and youth due to the overall decline of child health and…
PI: Shareck, Martine
People's health and well-being depend, in part, on the physical and social attributes of the neighbourhood where they live. If we want to design health promoting neighbourhoods, we need citizens, res…
The purpose of this request for a planning grant is to build a collaboration of researchers, trainees, community members and knowledge users focused on addressing health inequities experienced by the…
Air pollution is a leading risk factor for death and cardiorespiratory disease. Most Caribbean countries do not currently have established air pollution monitoring networks in place, and there have b…
PI: Brook, Jeffrey R; Fuller, Daniel L; Gauvin, Lise; Martin, Alberto; Subbarao, Padmaja
Beginning in 2015, eighteen $2M multi-year grants were awarded under the EHSI across three key areas: •Environments, Genes and Chronic Disease •Intersectoral Prevention Research, and •Environmental U…
Exploring health vulnerabilities to climate change: a participatory approach to research design
PI: Harrison, Mark; Apantaku, Glory O
In Canada, there is limited investment in policies that respond to the realities of a changing climate and its effect on population health. Given the direct and indirect effects of climate change tha…
PI: Lachowsky, Nathan J; Howard, Terry
HIV/AIDS is both a historical experience of loss and community resilience, and an ongoing public health concern for communities most impacted in Canada (e.g., gay men, Indigenous peoples, people of c…
PI: Bolduc, François; Moland, Mark
Public Health is key in translating the best research evidence and best practices into usable and actionable information for citizens in order to optimize population health. Considering the vast numb…