CIHR Projects
Browse 9 CIHR-funded research projects
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The membrane bilayer provides a partition between intracellular and extracellular compartments of organelles and cells. Membrane proteases have evolved to allow transfer of information across this pa…
The membrane bilayer provides a partition between intracellular and extracellular compartments of organelles and cells. Membrane proteases have evolved to allow transfer of information across this pa…
PI: Edgell, David R
A significant fraction of the genome of any organism is composed of mobile genetic elements, discrete units of nucleic acid that promote their own spread within and between genomes. Commonly referred…
Genes and gene products are regulated at multiple levels. Post-translational regulation by protein phosphorylation is of central importance in all cellular and developmental processes, in which prote…
Genes and gene products are regulated at multiple levels. Post-translational regulation by protein phosphorylation is of central importance in all cellular and developmental processes, in which prote…
Group II introns are a type of mobile DNA consisting of a self-splicing RNA and a reverse transcriptase (RT). Group II introns are found across the bacterial kingdom, including in many pathogens. Pre…
The central nervous system is generated from very few neurons (nerve cells) and attaining normal size and cell type diversity of this system requires tight control of how cells divide. Mutations in t…
The aim of this research is to determine how [NiFe]-hydrogenase enzymes are made in bacteria. These enzymes are found in many microorganisms, including the pathogenic bacteria Escherichia coli and He…
PI: Deber, Charles M
Embedded in the membranes of all living cells, membrane proteins are the molecular links between the inside and outside world. These proteins help preserve the biological structure of the cells; they…