CIHR Projects
Browse 21 CIHR-funded research projects
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PI: Ryder, Andrew G
East Asians in Canada are often stereotyped as a model minority, with few psychosocial difficulties. The reality is that mental health problems in this population are underestimated and often treated…
PI: Vallieres, Annie
Selon une étude récente, 14% des travailleurs de nuit et 8% des travailleurs à horaire rotatif souffrent du trouble du sommeil associé à leur horaire de travail. Des conséquences négatives importante…
PI: Lepage, Martin; Malla, Ashok K
People with a first episode of psychosis exhibit substantial heterogeneity with respect to severity and course over time. In the summer of 2004 and following the award of a CIHR operating grant we in…
PI: O'Connor, Kieron P; Lavoie, Marc E
Although Gilles de la Tourette syndrome (TS) is characterized by tics and diagnosed by the presence of tics, it is frequently accompanied by other behavioral problems such as obsessional compulsions …
Étude des facteurs psychosociaux impliqués dans le trouble du sommeil associé au travail de nuit.
PI: Vallieres, Annie
Selon une étude récente, 14% des travailleurs de nuit et 8% des travailleurs à horaire rotatif souffrent du trouble du sommeil associé à leur horaire de travail. Des conséquences négatives importante…
PI: Drolet, Guy
These experiments will help unravel the organization of opioid neuronal systems related to the stress response, and their role in adaptation to chronic stress. The relevance of the role(s) played by …
PI: Sullivan, Ronald
Stress-related psychiatric disorders like depression and anxiety are approximately twice as prevalent in women as men, yet the reasons for this discrepancy are not clear. The anatomical and neurochem…
PI: Borgeat, Pierre; Flamand, Louis
This research program is aimed at understanding how the body reacts to infection by viruses such as the Influenza virus, which is the pathological agent of flu. The Influenza virus causes a severe in…
Our research indicates that over 50% of breast cancer survivors may experience arm problems after treatment. These problems can be disabling, but few researchers have examined the impact of these cha…
PI: Lecomte, Tania; Corbière, Marc
More than 80% of individuals with a severe mental illness such as schizophrenia wish to work in regular competitive jobs. Even the best vocational programs --such as those following the supported emp…
PI: Carrier, Julie; Hebert, Marc
Seasonal affective disorder (SAD) is a condition characterized by cyclic fall and winter depression followed by spring and summer remission. Although the origin of the disorder is not known, the cons…
Schizophrenia is associated with three main classes of symptoms, termed positive, negative and cognitive symptoms. Positive symptoms such as hallucinations and delusions are well treated by modern an…
Impulsivity is a characteristic of human behavior that can be both beneficial and detrimental in our everyday lives. An impulsive decision can allow us to seize a valuable opportunity or make a disas…
PI: Armony, Jorge
The goal of this project is to explore the brain structures involved in the perception and memory of various types of emotional expressions, such as faces, vocalizations (e.g., laughs, cries) and mus…
PI: Yatham, Lakshmi N; Bond, David J
People with bipolar I disorder (BDI) expereince episodes of both mania and depression. Manic episodes are characterized by unusually elevated mood, increased energy, and impulsivity, to the point tha…
PI: Lam, Raymond W
Major depressive disorder (MDD) affects up to 15% of the Canadian population and is one of the leading causes of socioeconomic burden. There are many effective treatments for MDD including antidepres…
PI: Beaulieu, Martin
Monoamine neurotransmitters such as dopamine and serotonin are involved in the regulation of multiple brain functions including movement, mood and reward. Because of this, the biological mechanisms t…
The major objective of this proposal is to identify microRNA differences in prefrontal cortex and hippocampus of depressed suicides compared to controls. MicroRNA are small, noncoding RNA molecules t…
PI: Lau, Mark A
Depression is a potentially lifelong illness with a high relapse risk. The proposed study extends our research program studying the role of cognitive reactivity as a risk factor for depressive relaps…
PI: Leblanc, Vicki R; Regehr, Cheryl
Emergency services work is characterized by high stress situations requiring immediate intervention and by exposure to distressing events that are outside the experience of the general public. Dispat…
Mindfulness-based Cognitive Therapy for the prevention of depressive relapse in the workplace
PI: Lau, Mark A
Depression is among the most costly of all health problems to employers. This is particularly true for the health service sector, which typically employs mostly women as depression is twice as preval…