CIHR Projects

Browse 13 CIHR-funded research projects

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Showing 1-13 of 13 projects

PI: Man, S.F. Paul; Sin, Donald

Chronic Obstructive Pulmonary Disease is a very common chronic disease with huge societal and personal impact. This study will provide an integrated approach to create a bank of biomarkers (simple bl…

Other Respiratory Social / Cultural / Envi…
$367,795
Year: 2008
Population and Public Health
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PI: Becker, Allan B; Chan-Yeung, Moira

We undertook a multifaceted intervention program during the last trimester of pregnancy and the first twelve months of life in children at high risk for the development of asthma, based on a strong f…

Trial Respiratory Biomedical
$525,702
Year: 2008
Circulatory and Respiratory H…
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PI: Hamid, Qutayba A

Severe asthma is found in 10% of asthmatics but is responsible for a disproportionately high fraction of the health care budget. We have recently developed a program to identify difficult to treat as…

Other Respiratory Biomedical
$700,397
Year: 2008
Circulatory and Respiratory H…
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PI: Eurich, Dean; Majumdar, Sumit R

Pneumonia (serious infection of the lungs) is a common reason for hospitalization and in this day and age is still the 6th leading cause of death in Canada. Despite how common and costly it is, surpr…

Observational Respiratory Social / Cultural / Envi…
$135,785
Year: 2008
Population and Public Health
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PI: Rubin, Barry B

Bacterial infection of the lower respiratory tract is a common illness and is also a leading cause of death. It is estimated that 5.6 million cases of community acquired pneumonia are treated annuall…

Other Respiratory Biomedical
$388,518
Year: 2008
Infection and Immunity
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PI: Peever, John H

Obstructive sleep apnea (OSA) is the most common and severe sleep disorder. It affects more than 18 million North Americans and causes disturbed sleep, excessive sleepiness, high blood pressure, clog…

Other Respiratory Biomedical
$737,490
Year: 2008
Circulatory and Respiratory H…
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PI: Peever, John H

Obstructive sleep apnea (OSA) is the most common and severe sleep disorder. It affects more than 18 million North Americans and causes disturbed sleep, excessive sleepiness, high blood pressure, clog…

Other Respiratory Biomedical
$300,000
Year: 2008
Circulatory and Respiratory H…
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PI: Bacon, Simon L

Asthma is a chronic disorder of the airways primarily driven by increased airway inflammation, and is an escalating medical problem in Canada. For example, between 1994 and 2001 there was a 40% incre…

Trial Respiratory Clinical
$300,000
Year: 2008
Circulatory and Respiratory H…
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PI: Bacon, Simon L

Asthma is a chronic disorder of the airways primarily driven by increased airway inflammation, and is an escalating medical problem in Canada. For example, between 1994 and 2001 there was a 40% incre…

Trial Respiratory Clinical
$323,025
Year: 2008
Circulatory and Respiratory H…
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PI: Giembycz, Mark A

Phosphodiesterase (PDE) 4 inhibitors are a new class of drugs being developed for the treatment of chronic obstructive pulmonary disease (COPD), which is more commonly referred to as bronchitis and/o…

Other Respiratory Biomedical
$669,215
Year: 2008
Infection and Immunity
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PI: Keshavjee, Shaf

Lung transplantation (LTx) has become life saving therapy for patients suffering from many types of end-stage lung diseases (e.g. emphysema, pulmonary fibrosis, pulmonary hypertension and cystic fibr…

Other Respiratory Biomedical
$774,344
Year: 2008
Circulatory and Respiratory H…
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PI: Martin, James G

Asthma is caused by factors in the environment that act on the susceptible host, creating constriction of the airways or bronchospasm. The airways undergo changes after allergen exposure in sensitize…

Other Respiratory Biomedical
$770,088
Year: 2008
Circulatory and Respiratory H…
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PI: Debigare, Richard

Muscle wasting is a significant problem in chronic obstructive pulmonary disease (COPD) which is associated with important clinical issues such as decreased functional status, reduced quality of life…

Other Respiratory Biomedical
$225,985
Year: 2008
Musculoskeletal Health and Ar…
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